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The transcription factor complex LMO2/TAL1 regulates branching and endothelial cell migration in sprouting angiogenesis
The transcription factor complex, consisting of LMO2, TAL1 or LYL1, and GATA2, plays an important role in capillary sprouting by regulating VEGFR2, DLL4, and angiopoietin 2 in tip cells. Overexpression of the basic helix-loop-helix transcription factor LYL1 in transgenic mice results in shortened ta...
Autores principales: | Yamada, Yoshihiro, Zhong, Yi, Miki, Shiho, Taura, Akiko, Rabbitts, Terence H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068620/ https://www.ncbi.nlm.nih.gov/pubmed/35508511 http://dx.doi.org/10.1038/s41598-022-11297-3 |
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