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Reducing Chemotherapy-Induced DNA Damage via nAChR-Mediated Redox Reprograming—A New Mechanism for SCLC Chemoresistance Boosted by Nicotine

SIMPLE SUMMARY: Tobacco smoking is the dominant risk factor for lung cancer, particularly for small cell lung cancer (SCLC). Smoking is also associated with worse clinical outcomes of SCLC. For SCLC patients, platinum-based chemotherapy (cisplatin or carboplatin), in combination with etoposide, has...

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Detalles Bibliográficos
Autores principales:	Wang, Yuzhi, Bian, Tengfei, Song, Lina, Jiang, Yunhan, Huo, Zhiguang, Salloum, Ramzi G., Warren, Graham W., Kaye, Frederic J., Fujioka, Naomi, Jin, Lingtao, Xing, Chengguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100082/ https://www.ncbi.nlm.nih.gov/pubmed/35565402 http://dx.doi.org/10.3390/cancers14092272

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