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Targeting Myeloid Checkpoint Molecules in Combination With Antibody Therapy: A Novel Anti-Cancer Strategy With IgA Antibodies?
Immunotherapy with therapeutic antibodies has shown a lack of durable responses in some patients due to resistance mechanisms. Checkpoint molecules expressed by tumor cells have a deleterious impact on clinical responses to therapeutic antibodies. Myeloid checkpoints, which negatively regulate macro...
Autores principales: | Chan, Chilam, Lustig, Marta, Baumann, Niklas, Valerius, Thomas, van Tetering, Geert, Leusen, Jeanette H. W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295600/ https://www.ncbi.nlm.nih.gov/pubmed/35865547 http://dx.doi.org/10.3389/fimmu.2022.932155 |
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