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Lipidation of Naturally Occurring α-Helical Antimicrobial Peptides as a Promising Strategy for Drug Design
In this paper, we describe the chemical synthesis, preliminary evaluation of antimicrobial properties and mechanisms of action of a novel group of lipidated derivatives of three naturally occurring α-helical antimicrobial peptides, LL-I (VNWKKVLGKIIKVAK-NH(2)), LK6 (IKKILSKILLKKL-NH(2)), ATRA-1 (KRF...
Autores principales: | Makowska, Marta, Kosikowska-Adamus, Paulina, Zdrowowicz, Magdalena, Wyrzykowski, Dariusz, Prahl, Adam, Sikorska, Emilia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959048/ https://www.ncbi.nlm.nih.gov/pubmed/36835362 http://dx.doi.org/10.3390/ijms24043951 |
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