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Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl
Bcr/Abl is a chimeric oncogene that can cause both acute and chronic human leukemias. Bcr/Abl-encoded proteins exhibit elevated kinase activity compared to c-Abl, but the mechanisms of transformation are largely unknown. Some of the biological effects of Bcr/Abl overlap with those of hematopoietic c...
| Formato: | Texto |
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| Lenguaje: | English |
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The Rockefeller University Press
1996
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192351/ https://www.ncbi.nlm.nih.gov/pubmed/8642285 |