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Construction and functional analyses of a comprehensive σ(54) site-directed mutant library using alanine–cysteine mutagenesis
The σ(54) factor associates with core RNA polymerase (RNAP) to form a holoenzyme that is unable to initiate transcription unless acted on by an activator protein. σ(54) is closely involved in many steps of activator-dependent transcription, such as core RNAP binding, promoter recognition, activator...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715252/ https://www.ncbi.nlm.nih.gov/pubmed/19474350 http://dx.doi.org/10.1093/nar/gkp419 |