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Streptococcus pneumoniae Induces Autophagy through the Inhibition of the PI3K-I/Akt/mTOR Pathway and ROS Hypergeneration in A549 Cells

The present study focused on the action mechanism of S. pneumoniae (Sp) in inducing autophagy in human alveolar epithelial cells. Sp, a gram-positive extracellular bacterium, activates autophagy with considerably increased microtuble-associated protein light chain 3 (LC3) punctation in A549 cells. T...

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Detalles Bibliográficos
Autores principales:	Li, Pu, Shi, Jing, He, Qiao, Hu, Qin, Wang, Yun Ying, Zhang, Li Jun, Chan, Wai Ting, Chen, Wei-Xian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372526/ https://www.ncbi.nlm.nih.gov/pubmed/25803050 http://dx.doi.org/10.1371/journal.pone.0122753

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