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Hippocampal Insulin Resistance Impairs Spatial Learning and Synaptic Plasticity

Insulin receptors (IRs) are expressed in discrete neuronal populations in the central nervous system, including the hippocampus. To elucidate the functional role of hippocampal IRs independent of metabolic function, we generated a model of hippocampal-specific insulin resistance using a lentiviral v...

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Detalles Bibliográficos
Autores principales:	Grillo, Claudia A., Piroli, Gerardo G., Lawrence, Robert C., Wrighten, Shayna A., Green, Adrienne J., Wilson, Steven P., Sakai, Randall R., Kelly, Sandra J., Wilson, Marlene A., Mott, David D., Reagan, Lawrence P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2015
Materias:	Complications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613975/ https://www.ncbi.nlm.nih.gov/pubmed/26216852 http://dx.doi.org/10.2337/db15-0596

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