Cargando…
Structure of the Human Factor VIII C2 Domain in Complex with the 3E6 Inhibitory Antibody
Blood coagulation factor VIII is a glycoprotein cofactor that is essential for the intrinsic pathway of the blood coagulation cascade. Inhibitory antibodies arise either spontaneously or in response to therapeutic infusion of functional factor VIII into hemophilia A patients, many of which are speci...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657047/ https://www.ncbi.nlm.nih.gov/pubmed/26598467 http://dx.doi.org/10.1038/srep17216 |