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Protumoral TSP50 Regulates Macrophage Activities and Polarization via Production of TNF-α and IL-1β, and Activation of the NF-κB Signaling Pathway
Testes-specific protease 50 (TSP50) is abnormally overexpressed in many kinds of cancers and promotes cell proliferation and migration. However, whether TSP50 can influence the tumor microenvironment, especially the function of immune cells in the microenvironment, remains largely unknown. We demons...
Autores principales: | Yang, Cheng, Zhang, Dong-Mei, Song, Zhen-Bo, Hou, Ya-Qin, Bao, Yong-Li, Sun, Lu-Guo, Yu, Chun-Lei, Li, Yu-Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684331/ https://www.ncbi.nlm.nih.gov/pubmed/26684869 http://dx.doi.org/10.1371/journal.pone.0145095 |
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