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Parent-offspring regression to estimate the heritability of an HIV-1 trait in a realistic setup
BACKGROUND: Parent-offspring (PO) regression is a central tool to determine the heritability of phenotypic traits; i.e., the relative extent to which those traits are controlled by genetic factors. The applicability of PO regression to viral traits is unclear because the direction of viral transmiss...
Autores principales: | Bachmann, Nadine, Turk, Teja, Kadelka, Claus, Marzel, Alex, Shilaih, Mohaned, Böni, Jürg, Aubert, Vincent, Klimkait, Thomas, Leventhal, Gabriel E., Günthard, Huldrych F., Kouyos, Roger |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442860/ https://www.ncbi.nlm.nih.gov/pubmed/28535768 http://dx.doi.org/10.1186/s12977-017-0356-3 |
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