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Shifting meiotic to mitotic spindle assembly in oocytes disrupts chromosome alignment
Mitotic spindles assemble from two centrosomes, which are major microtubule‐organizing centers (MTOCs) that contain centrioles. Meiotic spindles in oocytes, however, lack centrioles. In mouse oocytes, spindle microtubules are nucleated from multiple acentriolar MTOCs that are sorted and clustered pr...
Autores principales: | Bennabi, Isma, Quéguiner, Isabelle, Kolano, Agnieszka, Boudier, Thomas, Mailly, Philippe, Verlhac, Marie‐Hélène, Terret, Marie‐Emilie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797964/ https://www.ncbi.nlm.nih.gov/pubmed/29330318 http://dx.doi.org/10.15252/embr.201745225 |
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