Novel NADPH oxidase inhibitor VAS2870 suppresses TGF-β-dependent epithelial-to-mesenchymal transition in retinal pigment epithelial cells

NADPH oxidases (NOXs) are important in the pathophysiology of fibrotic diseases. The expression and activity of NOXs are regulated by growth factors, including transforming growth factor (TGF-β). The proliferation of retinal pigment epithelial (RPE) cells following epithelial- to-mesenchymal transit...

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Detalles Bibliográficos
Autores principales: Yang, Jing, Li, Jing, Wang, Qun, Xing, Yao, Tan, Zizhu, Kang, Qianyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979836/
https://www.ncbi.nlm.nih.gov/pubmed/29620174
http://dx.doi.org/10.3892/ijmm.2018.3612

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