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PIM kinases mediate resistance of glioblastoma cells to TRAIL by a p62/SQSTM1-dependent mechanism

Glioblastoma (GBM) is the most common and aggressive brain tumor and is associated with poor prognosis. GBM cells are frequently resistant to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and finding new combinatorial therapies to sensitize glioma cells to TRAIL remains an importan...

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Detalles Bibliográficos
Autores principales:	Serrano-Saenz, Santiago, Palacios, Carmen, Delgado-Bellido, Daniel, López-Jiménez, Laura, Garcia-Diaz, Angel, Soto-Serrano, Yolanda, Casal, J. Ignacio, Bartolomé, Rubén A., Fernández-Luna, José Luis, López-Rivas, Abelardo, Oliver, F. Javier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362213/ https://www.ncbi.nlm.nih.gov/pubmed/30718520 http://dx.doi.org/10.1038/s41419-018-1293-3

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