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Caveolin-1 regulation of Sp1 controls production of the antifibrotic protein follistatin in kidney mesangial cells
BACKGROUND: We previously showed that caveolin-1 (cav-1), an integral membrane protein, is required for the synthesis of matrix proteins by glomerular mesangial cells (MC). In a previous study to understand how cav-1 is involved in regulating matrix production, we had identified significant upregula...
Autores principales: | Mehta, Neel, Zhang, Dan, Li, Renzhong, Wang, Tony, Gava, Agata, Parthasarathy, Pavithra, Gao, Bo, Krepinsky, Joan C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472091/ https://www.ncbi.nlm.nih.gov/pubmed/30995923 http://dx.doi.org/10.1186/s12964-019-0351-5 |
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