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Peripheral inflammation promotes brain tau transmission via disrupting blood–brain barrier
Abnormal aggregation of pathological tau protein is a neuropathological feature of Alzheimer’s disease (AD). In the AD patients, the abnormal tau accumulation first appeared in entorhinal cortex (EC) and then propagated to the hippocampus with microglia activation and inflammation, but the mechanism...
Autores principales: | Liu, Yanchao, Zhang, Shujuan, Li, Xiaoguang, Liu, Enjie, Wang, Xin, Zhou, Qiuzhi, Ye, Jinwang, Wang, Jian-Zhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033313/ https://www.ncbi.nlm.nih.gov/pubmed/32043530 http://dx.doi.org/10.1042/BSR20193629 |
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