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Acute inactivation of retromer and ESCPE-1 leads to time-resolved defects in endosomal cargo sorting
Human retromer, a heterotrimer of VPS26 (VPS26A or VPS26B), VPS35 and VPS29, orchestrates the endosomal retrieval of internalised cargo and promotes their cell surface recycling, a prototypical cargo being the glucose transporter GLUT1 (also known as SLC2A1). The role of retromer in the retrograde s...
Autores principales: | Evans, Ashley J., Daly, James L., Anuar, Anis N. K., Simonetti, Boris, Cullen, Peter J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7420817/ https://www.ncbi.nlm.nih.gov/pubmed/32747499 http://dx.doi.org/10.1242/jcs.246033 |
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