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Histone H3K9 Demethylase JMJD2B Plays a Role in LXRα-Dependent Lipogenesis

Ligand-activated liver X receptor α (LXRα) upregulates the expression of hepatic lipogenic genes, which leads to triglyceride (TG) accumulation, resulting in nonalcoholic fatty liver disease (NAFLD). Thus, LXRα regulation may provide a novel therapeutic target against NAFLD. However, histone methyla...

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Detalles Bibliográficos
Autores principales:	Kim, Ji-Hyun, Jung, Dae Young, Kim, Hye-Ran, Jung, Myeong Ho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664202/ https://www.ncbi.nlm.nih.gov/pubmed/33167594 http://dx.doi.org/10.3390/ijms21218313

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