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Meclozine ameliorates bone mineralization and growth plate structure in a mouse model of X‑linked hypophosphatemia

X-linked hypophosphatemic rickets (XLH) is characterized by hypo-mineralization of the bone due to hypophosphatemia. XLH is caused by abnormally high levels of fibroblast growth factor 23, which trigger renal phosphate wasting. Activated fibroblast growth factor receptor 3 (FGFR3) signaling is consi...

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Detalles Bibliográficos
Autores principales:	Kamiya, Yasunari, Matsushita, Masaki, Mishima, Kenichi, Ohkawara, Bisei, Michigami, Toshimi, Imagama, Shiro, Ohno, Kinji, Kitoh, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764053/ https://www.ncbi.nlm.nih.gov/pubmed/36569439 http://dx.doi.org/10.3892/etm.2022.11738

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