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Insights into the Regulation of TNF-α Production in Human Mononuclear Cells: The Effects of Non-Specific Phosphodiesterase Inhibition

OBJECTIVE: The objective of this study was to determine the effect of nonspecific phosphodiesterase inhibition on transcription factor activation and tumor necrosis factor-alpha (TNF-α) production in lipopolysaccharide (LPS)-stimulated human mononuclear cells. INTRODUCTION: The production of TNF-α f...

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Detalles Bibliográficos
Autores principales:	Deree, Jessica, Martins, Joilson O., Melbostad, Heidi, Loomis, William H., Coimbra, Raul
Formato:	Texto
Lenguaje:	English
Publicado:	Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2008
Materias:	Clinical Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664230/ https://www.ncbi.nlm.nih.gov/pubmed/18568240 http://dx.doi.org/10.1590/S1807-59322008000300006

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