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Intra-tumour genetic heterogeneity and poor chemoradiotherapy response in cervical cancer
BACKGROUND: Intra-tumour genetic heterogeneity has been reported in both leukaemias and solid tumours and is implicated in the development of drug resistance in CML and AML. The role of genetic heterogeneity in drug response in solid tumours is unknown. METHODS: To investigate intra-tumour genetic h...
Autores principales: | Cooke, S L, Temple, J, MacArthur, S, Zahra, M A, Tan, L T, Crawford, R A F, Ng, C K Y, Jimenez-Linan, M, Sala, E, Brenton, J D |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031882/ https://www.ncbi.nlm.nih.gov/pubmed/21063398 http://dx.doi.org/10.1038/sj.bjc.6605971 |
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