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Gpr177 Deficiency Impairs Mammary Development and Prohibits Wnt-Induced Tumorigenesis
Aberrant regulation of the Wnt pathway, essential for various developmental processes, is tightly linked to human breast cancers. By hijacking this evolutionary conserved signaling pathway, cancer cells acquire sustaining proliferation ability, leading to modification of physiologic properties neces...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574013/ https://www.ncbi.nlm.nih.gov/pubmed/23457599 http://dx.doi.org/10.1371/journal.pone.0056644 |