Cargando…

EGFR Mutation Analysis of Circulating Tumor DNA Using an Improved PNA-LNA PCR Clamp Method

Introduction. Rebiopsies have become more crucial in non-small cell lung cancer (NSCLC). Instead of invasive biopsies, development of collecting biological data of the tumor from blood samples is expected. We conducted a prospective study to assess the feasibility of detection of epidermal growth fa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Watanabe, Kana, Fukuhara, Tatsuro, Tsukita, Yoko, Morita, Mami, Suzuki, Aya, Tanaka, Nobuyuki, Terasaki, Hiroshi, Nukiwa, Toshihiro, Maemondo, Makoto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961805/ https://www.ncbi.nlm.nih.gov/pubmed/27478396 http://dx.doi.org/10.1155/2016/5297329

Ejemplares similares

DISSECT Method Using PNA-LNA Clamp Improves Detection of EGFR T790m Mutation
por: Guha, Minakshi, et al.
Publicado: (2013)

Characteristics and prognostic analysis of patients with detected KRAS mutations in resected lung adenocarcinomas by peptide nucleic acid-locked nucleic acid polymerase chain reaction (PNA-LNA PCR) clamp method
por: Hashimoto, Tatsuya, et al.
Publicado: (2023)

Development of a Detection System for ESR1 Mutations in Circulating Tumour DNA Using PNA-LNA-Mediated PCR Clamping
por: Kojima, Yuki, et al.
Publicado: (2023)

Detection of EGFR mutations in circulating free DNA by PNA-mediated PCR clamping
por: Kim, Hye-Ryoun, et al.
Publicado: (2013)

Monitoring of Plasma EGFR Mutations during Osimertinib Treatment for NSCLC Patients with Acquired T790M Mutation
por: Watanabe, Kana, et al.
Publicado: (2023)

Detection of Ultra-Rare ESR1 Mutations in Primary Breast Cancer Using LNA-Clamp ddPCR
por: Hashimoto, Yoko, et al.
Publicado: (2023)

Treatment with immune checkpoint inhibitors after EGFR‐TKIs in EGFR ‐mutated lung cancer
por: Ito, Takashi, et al.
Publicado: (2021)

Application of Locked Nucleic Acid (LNA) Primer and PCR Clamping by LNA Oligonucleotide to Enhance the Amplification of Internal Transcribed Spacer (ITS) Regions in Investigating the Community Structures of Plant–Associated Fungi
por: Ikenaga, Makoto, et al.
Publicado: (2016)

A Prospective Cohort Study Assessing the Relationship between Plasma Levels of Osimertinib and Treatment Efficacy and Safety
por: Fukuhara, Tatsuro, et al.
Publicado: (2023)

Disruption of Higher Order DNA Structures in Friedreich’s Ataxia (GAA)(n) Repeats by PNA or LNA Targeting
por: Bergquist, Helen, et al.
Publicado: (2016)

Non-Small-Cell Lung Cancer-Sensitive Detection of the p.Thr790Met EGFR Alteration by Preamplification before PNA-Mediated PCR Clamping and Pyrosequencing
por: Billaud, Amandine, et al.
Publicado: (2020)

Application of Locked Nucleic Acid (LNA) Oligonucleotide–PCR Clamping Technique to Selectively PCR Amplify the SSU rRNA Genes of Bacteria in Investigating the Plant-Associated Community Structures
por: Ikenaga, Makoto, et al.
Publicado: (2014)

Novel Methodology for Rapid Detection of KRAS Mutation Using PNA-LNA Mediated Loop-Mediated Isothermal Amplification
por: Itonaga, Masahiro, et al.
Publicado: (2016)

Evaluation of plasma EGFR mutation as an early predictor of response of erlotinib plus bevacizumab treatment in the NEJ026 study
por: Fukuhara, Tatsuro, et al.
Publicado: (2020)

Improvements in Bacterial Primers to Enhance Selective SSU rRNA Gene Amplification of Plant-associated Bacteria by Applying the LNA Oligonucleotide-PCR Clamping Technique
por: Ikenaga, Makoto, et al.
Publicado: (2018)

Detection of Ki-ras mutations in tissue and plasma samples of patients with pancreatic cancer using PNA-mediated PCR clamping and hybridisation probes
por: Däbritz, J, et al.
Publicado: (2005)

Detection of K-Ras mutations in tumour samples of patients with non-small cell lung cancer using PNA-mediated PCR clamping
por: Beau-Faller, M, et al.
Publicado: (2009)

Detection of SF3B1 p.Lys700Glu Mutation by PNA-PCR Clamping in Myelodysplastic Syndromes and Myeloproliferative Neoplasms
por: Petiti, Jessica, et al.
Publicado: (2022)

PNA Clamping in Nucleic Acid Amplification Protocols to Detect Single Nucleotide Mutations Related to Cancer
por: Fouz, Munira F., et al.
Publicado: (2020)

Potential of combination therapy in EGFR mutated lung cancer
por: Maemondo, Makoto
Publicado: (2020)

PNA clamping-assisted fluorescence melting curve analysis for detecting EGFR and KRAS mutations in the circulating tumor DNA of patients with advanced non-small cell lung cancer
por: Han, Ji-Youn, et al.
Publicado: (2016)

Detection of activating and acquired resistant mutation in plasma from EGFR-mutated NSCLC patients by peptide nucleic acid (PNA) clamping-assisted fluorescence melting curve analysis
por: Kim, Chang Gon, et al.
Publicado: (2017)

Large-scale expansions of Friedreich's ataxia GAA•TTC repeats in an experimental human system: role of DNA replication and prevention by LNA-DNA oligonucleotides and PNA oligomers
por: Rastokina, Anastasia, et al.
Publicado: (2023)

Jumping the green wall: The use of PNA‐DNA clamps to enhance microbiome sampling depth in wildlife microbiome research
por: Víquez‐R, Luis, et al.
Publicado: (2020)

Erratum to: PNA clamping-assisted fluorescence melting curve analysis for detecting EGFR and KRAS mutations in the circulating tumor DNA of patients with advanced non-small cell lung cancer
por: Han, Ji-Youn, et al.
Publicado: (2016)

Detection of BRAF, NRAS, KIT, GNAQ, GNA11 and MAP2K1/2 mutations in Russian melanoma patients using LNA PCR clamp and biochip analysis
por: Emelyanova, Marina, et al.
Publicado: (2017)

Updated survival outcomes of NEJ005/TCOG0902: a randomised phase II study of concurrent versus sequential alternating gefitinib and chemotherapy in previously untreated non-small cell lung cancer with sensitive EGFR mutations
por: Oizumi, Satoshi, et al.
Publicado: (2018)

Effectiveness of blocking primers and a peptide nucleic acid (PNA) clamp for 18S metabarcoding dietary analysis of herbivorous fish
por: Homma, Chiho, et al.
Publicado: (2022)

Standardization of an LNA-based TaqMan assay qPCR analysis for Aspiculuris tetraptera DNA in mouse faeces
por: Isayama, Keishiro, et al.
Publicado: (2020)

Comparison of Direct Sequencing, PNA Clamping-Real Time Polymerase Chain Reaction, and Pyrosequencing Methods for the Detection of EGFR Mutations in Non-small Cell Lung Carcinoma and the Correlation with Clinical Responses to EGFR Tyrosine Kinase Inhibitor Treatment
por: Lee, Hyun Ju, et al.
Publicado: (2013)

Updated Analysis of NEJ009: Gefitinib-Alone Versus Gefitinib Plus Chemotherapy for Non–Small-Cell Lung Cancer With Mutated EGFR
por: Miyauchi, Eisaku, et al.
Publicado: (2022)

Position-dependent effects of locked nucleic acid (LNA) on DNA sequencing and PCR primers
por: Levin, Joshua D., et al.
Publicado: (2006)

Fluorogenic PNA probes
por: Vilaivan, Tirayut
Publicado: (2018)

A Novel, Highly Selective RT-QPCR Method for Quantification of MSRV Using PNA Clamping Syncytin-1 (ERVWE1)
por: Machnik, Grzegorz, et al.
Publicado: (2015)

Unwinding the SARS-CoV-2 Ribosomal Frameshifting Pseudoknot with LNA and G-Clamp-Modified Phosphorothioate Oligonucleotides Inhibits Viral Replication
por: Knizhnik, Ekaterina, et al.
Publicado: (2023)

Targeting LDL Cholesterol With LNA
por: Krieg, Arthur M
Publicado: (2012)

Applications of PNA-Based Artificial Restriction DNA Cutters
por: Shigi, Narumi, et al.
Publicado: (2017)

The first crystal structures of RNA–PNA duplexes and a PNA-PNA duplex containing mismatches—toward anti-sense therapy against TREDs
por: Kiliszek, Agnieszka, et al.
Publicado: (2016)

Synthesis of PNA Oligoether Conjugates
por: Ghidini, Alice, et al.
Publicado: (2014)

Clinical implications of PNA‑sequencing as a complementary test for EGFR mutation analysis in human lung cancer
por: Chen, Yi-Lin, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_lai6ivpnk4i0v7ppuquhn3jkg8