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Tetrandrine, an Activator of Autophagy, Induces Autophagic Cell Death via PKC-α Inhibition and mTOR-Dependent Mechanisms
Emerging evidence suggests the therapeutic role of autophagic modulators in cancer therapy. This study aims to identify novel traditional Chinese medicinal herbs as potential anti-tumor agents through autophagic induction, which finally lead to autophagy mediated-cell death in apoptosis-resistant ca...
Autores principales: | Wong, Vincent Kam Wai, Zeng, Wu, Chen, Juan, Yao, Xiao Jun, Leung, Elaine Lai Han, Wang, Qian Qian, Chiu, Pauline, Ko, Ben C. B., Law, Betty Yuen Kwan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462963/ https://www.ncbi.nlm.nih.gov/pubmed/28642707 http://dx.doi.org/10.3389/fphar.2017.00351 |
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