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Enhanced Cell Killing by Overexpression of Dominant‐negative Phosphatidylinositol 3‐Kinase Subunit, Δp85, Following Genotoxic Stresses
Phosphatidylinositol 3‐kinase (PI3‐K) is a heterodimer of a regulatory subunit, p85, and a catalytic subunit, p110. A number of previous reports showed that PI3‐K functions in diverse cellular phenomena such as cell proliferation, glucose catabolism, cell adhesion, and vesicle transport. It is also...
Autores principales: | Tachiiri, Seiji, Sasai, Keisuke, Oya, Natsuo, Hiraoka, Masahiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926311/ https://www.ncbi.nlm.nih.gov/pubmed/11123431 http://dx.doi.org/10.1111/j.1349-7006.2000.tb00919.x |
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