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Lentivirus-mediated siRNA knockdown of SPHK1 inhibits proliferation and tumorigenesis of neuroblastoma
BACKGROUND: The overexpression of sphingosine kinase 1 (SPHK1) is responsible for the progress of many cancers. However, the role of SPHK1 in the development and progression of neuroblastoma (NB) remain largely unknown. Here in this study, we explored whether silencing SPHK1 by lentivirus-mediated s...
Autores principales: | Su, Lin, Tian, Junyan, Sun, Jinsong, Han, Nuan, Feng, Lin, Yu, Baohua, Wang, Yuepeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203087/ https://www.ncbi.nlm.nih.gov/pubmed/30425511 http://dx.doi.org/10.2147/OTT.S180962 |
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