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Development and Evaluation of Docetaxel-Phospholipid Complex Loaded Self-Microemulsifying Drug Delivery System: Optimization and In Vitro/Ex Vivo Studies
Docetaxel (DTX) has clinical efficacy in the treatment of breast cancer, but it is difficult to develop a product for oral administration, due to low solubility and permeability. This study focused on preparing a self-microemulsifying drug delivery system (SME) loaded with DTX-phospholipid complex (...
Autores principales: | Wang, Miao, You, Sung-Kyun, Lee, Hong-Ki, Han, Min-Gu, Lee, Hyeon-Min, Pham, Thi Mai Anh, Na, Young-Guk, Cho, Cheong-Weon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357111/ https://www.ncbi.nlm.nih.gov/pubmed/32545452 http://dx.doi.org/10.3390/pharmaceutics12060544 |
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