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Diagnostic value of skin RT-QuIC in Parkinson’s disease: a two-laboratory study
Skin α-synuclein deposition is considered a potential biomarker for Parkinson’s disease (PD). Real-time quaking-induced conversion (RT-QuIC) is a novel, ultrasensitive, and efficient seeding assay that enables the detection of minute amounts of α-synuclein aggregates. We aimed to determine the diagn...
Autores principales: | Kuzkina, Anastasia, Bargar, Connor, Schmitt, Daniela, Rößle, Jonas, Wang, Wen, Schubert, Anna-Lena, Tatsuoka, Curtis, Gunzler, Steven A., Zou, Wen-Quan, Volkmann, Jens, Sommer, Claudia, Doppler, Kathrin, Chen, Shu G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593128/ https://www.ncbi.nlm.nih.gov/pubmed/34782640 http://dx.doi.org/10.1038/s41531-021-00242-2 |
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