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The influence of 4-thiouridine labeling on pre-mRNA splicing outcomes
Metabolic labeling is a widely used tool to investigate different aspects of pre-mRNA splicing and RNA turnover. The labeling technology takes advantage of native cellular machineries where a nucleotide analog is readily taken up and incorporated into nascent RNA. One such analog is 4-thiouridine (4...
Autores principales: | Altieri, Jessie A. C., Hertel, Klemens J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668116/ https://www.ncbi.nlm.nih.gov/pubmed/34898625 http://dx.doi.org/10.1371/journal.pone.0257503 |
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