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Altered proteome in translation initiation fidelity defective eIF5(G31R) mutant causes oxidative stress and DNA damage
The recognition of the AUG start codon and selection of an open reading frame (ORF) is fundamental to protein biosynthesis. Defect in the fidelity of start codon selection adversely affect proteome and have a pleiotropic effect on cellular function. Using proteomic techniques, we identified differen...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943034/ https://www.ncbi.nlm.nih.gov/pubmed/35322093 http://dx.doi.org/10.1038/s41598-022-08857-y |