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Defective lysosomal acidification: a new prognostic marker and therapeutic target for neurodegenerative diseases

Lysosomal acidification dysfunction has been implicated as a key driving factor in the pathogenesis of neurodegenerative diseases, including Alzheimer’s disease and Parkinson’s disease. Multiple genetic factors have been linked to lysosomal de-acidification through impairing the vacuolar-type ATPase...

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Detalles Bibliográficos
Autores principales:	Lo, Chih Hung, Zeng, Jialiu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249214/ https://www.ncbi.nlm.nih.gov/pubmed/37287072 http://dx.doi.org/10.1186/s40035-023-00362-0

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