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Defective lysosomal acidification: a new prognostic marker and therapeutic target for neurodegenerative diseases
Lysosomal acidification dysfunction has been implicated as a key driving factor in the pathogenesis of neurodegenerative diseases, including Alzheimer’s disease and Parkinson’s disease. Multiple genetic factors have been linked to lysosomal de-acidification through impairing the vacuolar-type ATPase...
Autores principales: | Lo, Chih Hung, Zeng, Jialiu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249214/ https://www.ncbi.nlm.nih.gov/pubmed/37287072 http://dx.doi.org/10.1186/s40035-023-00362-0 |
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