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XRCC1 interacts with the p58 subunit of DNA Pol α-primase and may coordinate DNA repair and replication during S phase
Repair of single-stranded DNA breaks before DNA replication is critical in maintaining genomic stability; however, how cells deal with these lesions during S phase is not clear. Using combined approaches of proteomics and in vitro and in vivo protein–protein interaction, we identified the p58 subuni...
Autores principales: | Lévy, Nicolas, Oehlmann, Maren, Delalande, François, Nasheuer, Heinz Peter, Van Dorsselaer, Alain, Schreiber, Valérie, de Murcia, Gilbert, Ménissier-de Murcia, Josiane, Maiorano, Domenico, Bresson, Anne |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691816/ https://www.ncbi.nlm.nih.gov/pubmed/19305001 http://dx.doi.org/10.1093/nar/gkp144 |
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