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Rapid, modular and reliable construction of complex mammalian gene circuits
We developed a framework for quick and reliable construction of complex gene circuits for genetically engineering mammalian cells. Our hierarchical framework is based on a novel nucleotide addressing system for defining the position of each part in an overall circuit. With this framework, we demonst...
Autores principales: | Guye, Patrick, Li, Yinqing, Wroblewska, Liliana, Duportet, Xavier, Weiss, Ron |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763561/ https://www.ncbi.nlm.nih.gov/pubmed/23847100 http://dx.doi.org/10.1093/nar/gkt605 |
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