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Transient DNMT1 suppression reveals hidden heritable marks in the genome
Genome-wide demethylation and remethylation of DNA during early embryogenesis is essential for development. Imprinted germline differentially methylated domains (gDMDs) established by sex-specific methylation in either male or female germ cells, must escape these dynamic changes and sustain precise...
Autores principales: | McGraw, Serge, Zhang, Jacques X., Farag, Mena, Chan, Donovan, Caron, Maxime, Konermann, Carolin, Oakes, Christopher C., Mohan, K. Naga, Plass, Christoph, Pastinen, Tomi, Bourque, Guillaume, Chaillet, J. Richard, Trasler, Jacquetta M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330356/ https://www.ncbi.nlm.nih.gov/pubmed/25578964 http://dx.doi.org/10.1093/nar/gku1386 |
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