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Bid Regulates the Pathogenesis of Neurotropic Reovirus
Reovirus infection leads to apoptosis in both cultured cells and the murine central nervous system (CNS). NF-κB-driven transcription of proapoptotic cellular genes is required for the effector phase of the apoptotic response. Although both extrinsic death-receptor signaling pathways and intrinsic pa...
Autores principales: | Danthi, Pranav, Pruijssers, Andrea J., Berger, Angela K., Holm, Geoffrey H., Zinkel, Sandra S., Dermody, Terence S. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895667/ https://www.ncbi.nlm.nih.gov/pubmed/20617182 http://dx.doi.org/10.1371/journal.ppat.1000980 |
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