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QSAR Study and Molecular Design of Open-Chain Enaminones as Anticonvulsant Agents
Present work employs the QSAR formalism to predict the ED(50) anticonvulsant activity of ringed-enaminones, in order to apply these relationships for the prediction of unknown open-chain compounds containing the same types of functional groups in their molecular structure. Two different modeling app...
Autores principales: | Garro Martinez, Juan C., Duchowicz, Pablo R., Estrada, Mario R., Zamarbide, Graciela N., Castro, Eduardo A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257134/ https://www.ncbi.nlm.nih.gov/pubmed/22272137 http://dx.doi.org/10.3390/ijms12129354 |
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