Cargando…
Microbiota-Specific CD4CD8αα Tregs: Role in Intestinal Immune Homeostasis and Implications for IBD
In studies in murine models, active suppression by IL-10-secreting Foxp3 regulatory T cells (Tregs) has emerged as an essential mechanism in colon homeostasis. However, the role of the equivalent subset in humans remains unclear, leading to suggestions that other subsets and/or mechanisms may substi...
Autores principales: | Sarrabayrouse, Guillaume, Alameddine, Joudy, Altare, Frédéric, Jotereau, Francine |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597122/ https://www.ncbi.nlm.nih.gov/pubmed/26500657 http://dx.doi.org/10.3389/fimmu.2015.00522 |
Ejemplares similares
-
CD4CD8αα Lymphocytes, A Novel Human Regulatory T Cell Subset Induced by Colonic Bacteria and Deficient in Patients with Inflammatory Bowel Disease
por: Sarrabayrouse, Guillaume, et al.
Publicado: (2014) -
Faecalibacterium prausnitzii Skews Human DC to Prime IL10-Producing T Cells Through TLR2/6/JNK Signaling and IL-10, IL-27, CD39, and IDO-1 Induction
por: Alameddine, Joudy, et al.
Publicado: (2019) -
Human gut microbiota-reactive DP8α regulatory T cells, signature and related emerging functions
por: Jotereau, Francine, et al.
Publicado: (2022) -
Innate CD8αα(+) cells promote ILC1-like intraepithelial lymphocyte homeostasis and intestinal inflammation
por: Nazmi, Ali, et al.
Publicado: (2019) -
Control of CD8αα intestinal intraepithelial lymphocyte development by TGF-β
por: Konkel, Joanne E., et al.
Publicado: (2011)