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Vaccinia Virus Protein C6 Inhibits Type I IFN Signalling in the Nucleus and Binds to the Transactivation Domain of STAT2
The type I interferon (IFN) response is a crucial innate immune signalling pathway required for defense against viral infection. Accordingly, the great majority of mammalian viruses possess means to inhibit this important host immune response. Here we show that vaccinia virus (VACV) strain Western R...
Autores principales: | Stuart, Jennifer H., Sumner, Rebecca P., Lu, Yongxu, Snowden, Joseph S., Smith, Geoffrey L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131898/ https://www.ncbi.nlm.nih.gov/pubmed/27907166 http://dx.doi.org/10.1371/journal.ppat.1005955 |
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