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Regulator of G-Protein Signaling (RGS) Protein Modulation of Opioid Receptor Signaling as a Potential Target for Pain Management

Opioid drugs are the gold standard for the management of pain, but their use is severely limited by dangerous and unpleasant side effects. All clinically available opioid analgesics bind to and activate the mu-opioid receptor (MOR), a heterotrimeric G-protein-coupled receptor, to produce analgesia....

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Detalles Bibliográficos
Autores principales:	Senese, Nicolas B., Kandasamy, Ram, Kochan, Kelsey E., Traynor, John R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992652/ https://www.ncbi.nlm.nih.gov/pubmed/32038168 http://dx.doi.org/10.3389/fnmol.2020.00005

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