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LPS aggravates lung inflammation induced by RSV by promoting the ERK-MMP-12 signaling pathway in mice

BACKGROUND: RSV can lead to persistent airway inflammation and airway hyperresponsiveness (AHR), and is intimately associated with childhood recurrent wheezing and asthma, but the underlying mechanisms remain unclear. Lipopolysaccharide (LPS) is also implicated in the onset and exacerbation of asthm...

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Detalles Bibliográficos
Autores principales:	Chen, Shenglin, Xie, Jun, Zhao, Keting, Ren, Luo, Deng, Yu, Xie, Xiaohong, Chen, Shiyi, Xu, Hongmei, Long, Xiaoru, Liu, Enmei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372760/ https://www.ncbi.nlm.nih.gov/pubmed/32693803 http://dx.doi.org/10.1186/s12931-020-01453-6

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