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LPS aggravates lung inflammation induced by RSV by promoting the ERK-MMP-12 signaling pathway in mice
BACKGROUND: RSV can lead to persistent airway inflammation and airway hyperresponsiveness (AHR), and is intimately associated with childhood recurrent wheezing and asthma, but the underlying mechanisms remain unclear. Lipopolysaccharide (LPS) is also implicated in the onset and exacerbation of asthm...
Autores principales: | Chen, Shenglin, Xie, Jun, Zhao, Keting, Ren, Luo, Deng, Yu, Xie, Xiaohong, Chen, Shiyi, Xu, Hongmei, Long, Xiaoru, Liu, Enmei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372760/ https://www.ncbi.nlm.nih.gov/pubmed/32693803 http://dx.doi.org/10.1186/s12931-020-01453-6 |
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