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Repurposing Halicin as a potent covalent inhibitor for the SARS-CoV-2 main protease
The rapid spread of COVID-19 has caused a worldwide public health crisis. For prompt and effective development of antivirals for SARS-CoV-2, the pathogen of COVID-19, drug repurposing has been broadly conducted by targeting the main protease (M(Pro)), a key enzyme responsible for the replication of...
Autores principales: | Yang, Kai S., Alex Kuo, Syuan-Ting, Blankenship, Lauren R., Geng, Zhi Zachary, Li, Shuhua G., Russell, David H., Yan, Xin, Xu, Shiqing, Liu, Wenshe Ray |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s). Published by Elsevier B.V.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9023366/ https://www.ncbi.nlm.nih.gov/pubmed/35815070 http://dx.doi.org/10.1016/j.crchbi.2022.100025 |
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