Role of Stereochemistry on the Biological Activity of Nature-Inspired 3-Br-Acivicin Isomers and Derivatives

Chiral natural compounds are often biosynthesized in an enantiomerically pure fashion, and stereochemistry plays a pivotal role in biological activity. Herein, we investigated the significance of chirality for nature-inspired 3-Br-acivicin (3-BA) and its derivatives. The three unnatural isomers of 3...

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Detalles Bibliográficos
Autores principales: Galbiati, Andrea, Zana, Aureliano, Borsari, Chiara, Persico, Marco, Bova, Stefania, Tkachuk, Oleh, Corfu, Alexandra Ioana, Tamborini, Lucia, Basilico, Nicoletta, Fattorusso, Caterina, Bruno, Stefano, Parapini, Silvia, Conti, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095986/
https://www.ncbi.nlm.nih.gov/pubmed/37049935
http://dx.doi.org/10.3390/molecules28073172

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