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Lipopolysaccharide Preconditioning Restricts Microglial Overactivation and Alleviates Inflammation-Induced Depressive-like Behavior in Mice
Overactive microglia and severe neuroinflammation play crucial roles in the development of major depressive disorder. Preconditioning with lipopolysaccharide (LPS) provides protection against severe neuroinflammation. However, administering high doses of LPS to mice triggers depressive symptoms. The...
Autores principales: | Yu, Haiping, Kan, Junli, Tang, Mingming, Zhu, Yanbing, Hu, Baoyang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10137116/ https://www.ncbi.nlm.nih.gov/pubmed/37190515 http://dx.doi.org/10.3390/brainsci13040549 |
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