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Efficient Reprogramming of Mouse Fibroblasts to Neuronal Cells including Dopaminergic Neurons
Somatic cells were directly converted to functional neurons through the use of a combination of transcription factors, including Ascl1, Brn2, and Myt1l. However, a major limitation is the lack of a reliable source of cell-replacement therapy for neurological diseases. Here, we show that a combinatio...
Autores principales: | Oh, Seung-ick, Park, Hang-soo, Hwang, Insik, Park, Han-kyul, Choi, Kyung-Ah, Jeong, Hyesun, Kim, Suhng Wook, Hong, Sunghoi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058809/ https://www.ncbi.nlm.nih.gov/pubmed/24991651 http://dx.doi.org/10.1155/2014/957548 |
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