The Incorporation of Ribonucleotides Induces Structural and Conformational Changes in DNA

Ribonucleotide incorporation is the most common error occurring during DNA replication. Cells have hence developed mechanisms to remove ribonucleotides from the genome and restore its integrity. Indeed, the persistence of ribonucleotides into DNA leads to severe consequences, such as genome instabil...

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Detalles Bibliográficos
Autores principales: Meroni, Alice, Mentegari, Elisa, Crespan, Emmanuele, Muzi-Falconi, Marco, Lazzaro, Federico, Podestà, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2017
Materias:
Nucleic Acids and Genome Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627062/
https://www.ncbi.nlm.nih.gov/pubmed/28978432
http://dx.doi.org/10.1016/j.bpj.2017.07.013

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