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CD4 T cells react to local increase of α-synuclein in a pathology-associated variant-dependent manner and modify brain microglia in absence of brain pathology
We have previously shown that immunological processes in the brain during α-synuclein-induced neurodegeneration vary depending on the presence or absence of cell death. This suggests that the immune system is able to react differently to the different stages of α-synuclein pathology. However, it was...
Autores principales: | Olesen, Mads N., Christiansen, Josefine R., Petersen, Steen Vang, Jensen, Poul Henning, Paslawski, Wojciech, Romero-Ramos, Marina, Sanchez-Guajardo, Vanesa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857520/ https://www.ncbi.nlm.nih.gov/pubmed/29560431 http://dx.doi.org/10.1016/j.heliyon.2018.e00513 |
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