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Inhibition of mTORC1 by lncRNA H19 via disrupting 4E-BP1/Raptor interaction in pituitary tumours
Aberrant expression of long noncoding RNA H19 has been associated with tumour progression, but the underlying molecular tumourigenesis mechanisms remain largely unknown. Here, we report that H19 expression is frequently downregulated in human primary pituitary adenomas and is negatively correlated w...
Autores principales: | Wu, Ze Rui, Yan, Lichong, Liu, Yan Ting, Cao, Lei, Guo, Yu Hang, Zhang, Yong, Yao, Hong, Cai, Lin, Shang, Han Bing, Rui, Wei Wei, Yang, Gang, Zhang, Xiao Biao, Tang, Hao, Wang, Yu, Huang, Jin Yan, Wei, Yong Xu, Zhao, Wei Guo, Su, Bing, Wu, Zhe Bao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218470/ https://www.ncbi.nlm.nih.gov/pubmed/30397197 http://dx.doi.org/10.1038/s41467-018-06853-3 |
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