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New prodrugs of Adefovir and Cidofovir
New Adefovir (PMEA) prodrugs with a pro-moiety consisting of decyl or decyloxyethyl chain bearing hydroxyl function(s), hexaethyleneglycol or a (5-methyl-2-oxo-1,3-dioxolen-4-yl)methyl unit were prepared starting from the tetrabutylammonium salt of the phosphonate drug and an appropriate alkyl bromi...
Autores principales: | Tichý, Tomáš, Andrei, Graciela, Dračínský, Martin, Holý, Antonín, Balzarini, Jan, Snoeck, Robert, Krečmerová, Marcela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127853/ https://www.ncbi.nlm.nih.gov/pubmed/21565516 http://dx.doi.org/10.1016/j.bmc.2011.04.016 |
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