Cargando…

Silencing of MEF2D by siRNA Loaded Selenium Nanoparticles for Ovarian Cancer Therapy

BACKGROUND: Delivery of therapeutic small interfering RNA (siRNA) via functionalized nanoparticles holds great promise for cancer therapy. However, developing a safe and efficient delivery carrier of siRNA is a challenging issue. METHODS: RGDfC peptide was used to modify the surface of selenium nano...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Changbing, Xia, Yu, Huo, Shaochuan, Shou, Diwen, Mei, Qing, Tang, Wenjuan, Li, Yinghua, Liu, Hongsheng, Zhou, Yongjian, Zhu, Bing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723231/ https://www.ncbi.nlm.nih.gov/pubmed/33304100 http://dx.doi.org/10.2147/IJN.S270441

Ejemplares similares

Functionalized selenium nanoparticles for targeted siRNA delivery silence Derlin1 and promote antitumor efficacy against cervical cancer
por: Xia, Yu, et al.
Publicado: (2019)

Engineering siRNA-loaded and RGDfC-targeted selenium nanoparticles for highly efficient silencing of DCBLD2 gene for colorectal cancer treatment
por: Huang, Hongli, et al.
Publicado: (2023)

siRNA-loaded selenium nanoparticle modified with hyaluronic acid for enhanced hepatocellular carcinoma therapy
por: Xia, Yu, et al.
Publicado: (2018)

Inhibition of Enterovirus 71 by Selenium Nanoparticles Loaded with siRNA through Bax Signaling Pathways
por: Lin, Zhengfang, et al.
Publicado: (2020)

Folate-targeted selenium nanoparticles deliver therapeutic siRNA to improve hepatocellular carcinoma therapy
por: Xia, Yu, et al.
Publicado: (2018)

Multifunctional selenium nanoparticles as carriers of HSP70 siRNA to induce apoptosis of HepG2 cells
por: Li, Yinghua, et al.
Publicado: (2016)

Tumor-targeted delivery of siRNA to silence Sox2 gene expression enhances therapeutic response in hepatocellular carcinoma
por: Xia, Yu, et al.
Publicado: (2020)

Novel functionalized nanoparticles for tumor-targeting co-delivery of doxorubicin and siRNA to enhance cancer therapy
por: Xia, Yu, et al.
Publicado: (2017)

Targeted delivery of HES5-siRNA with novel polypeptide-modified nanoparticles for hepatocellular carcinoma therapy
por: Xia, Yu, et al.
Publicado: (2018)

Polymerized Selenium Nanoparticles for Folate-Receptor-Targeted Delivery of Anti-Luc-siRNA: Potential for Gene Silencing
por: Maiyo, Fiona, et al.
Publicado: (2020)

siRNA-Loaded Hydroxyapatite Nanoparticles for KRAS Gene Silencing in Anti-Pancreatic Cancer Therapy
por: Luo, Dandan, et al.
Publicado: (2021)

Therapeutic siRNA silencing in inflammatory monocytes
por: Leuschner, Florian, et al.
Publicado: (2011)

Nanocarriers for delivery of siRNA as gene silencing mediator
por: Morales-Becerril, Aideé, et al.
Publicado: (2022)

Macrophage‐targeted delivery of siRNA to silence Mecp2 gene expression attenuates pulmonary fibrosis
por: Mou, Yong, et al.
Publicado: (2022)

Effects of PEG anchors in PEGylated siRNA lipoplexes on in vitro gene-silencing effects and siRNA biodistribution in mice
por: Hattori, Yoshiyuki, et al.
Publicado: (2020)

In vivo silencing of alpha-synuclein using naked siRNA
por: Lewis, Jada, et al.
Publicado: (2008)

High potency silencing by single-stranded boranophosphate siRNA
por: Hall, Allison H. S., et al.
Publicado: (2006)

Primary and Secondary siRNAs in Geminivirus-induced Gene Silencing
por: Aregger, Michael, et al.
Publicado: (2012)

Chitosan Hydrogel as siRNA vector for prolonged gene silencing
por: Ma, Zhiwei, et al.
Publicado: (2014)

siRNA Versus miRNA as Therapeutics for Gene Silencing
por: Lam, Jenny K W, et al.
Publicado: (2015)

Strategies for Improving siRNA-Induced Gene Silencing Efficiency
por: Safari, Fatemeh, et al.
Publicado: (2017)

Identification of Novel Fibrosis Modifiers by In Vivo siRNA Silencing
por: Vollmann, Elisabeth H., et al.
Publicado: (2017)

Lipid Nanoparticle Delivery of siRNA to Silence Neuronal Gene Expression in the Brain
por: Rungta, Ravi L, et al.
Publicado: (2013)

Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo**
por: Jayaraman, Muthusamy, et al.
Publicado: (2012)

Nanoparticle-encapsulated siRNAs for gene silencing in the haematopoietic stem-cell niche
por: Krohn-Grimberghe, Marvin, et al.
Publicado: (2020)

Effect of AQP-5 silencing by siRNA interference on chemosensitivity of breast cancer cells
por: Li, Xueqing, et al.
Publicado: (2018)

RORC2 Gene Silencing in Human Th17 Cells by siRNA: Design and Evaluation of Highly Efficient siRNA
por: Hakemi, Mazdak Ganjalikhani, et al.
Publicado: (2013)

Restriction of H1N1 influenza virus infection by selenium nanoparticles loaded with ribavirin via resisting caspase-3 apoptotic pathway
por: Lin, Zhengfang, et al.
Publicado: (2018)

GW body disassembly triggered by siRNAs independently of their silencing activity
por: Serman, A., et al.
Publicado: (2007)

The Role of the Arabidopsis Exosome in siRNA–Independent Silencing of Heterochromatic Loci
por: Shin, Jun-Hye, et al.
Publicado: (2013)

Dendrimers as Carriers for siRNA Delivery and Gene Silencing: A Review
por: Wu, Jiangyu, et al.
Publicado: (2013)

Differences in silencing of mismatched targets by sliced versus diced siRNAs
por: Sun, Guihua, et al.
Publicado: (2018)

SiRNA silencing efficacy prediction based on a deep architecture
por: Han, Ye, et al.
Publicado: (2018)

Nuclear-targeted siRNA delivery for long-term gene silencing
por: Li, Na, et al.
Publicado: (2017)

siRNA Design to Silence the 3′UTR Region of Zika Virus
por: Perez-Mendez, María, et al.
Publicado: (2020)

Pathways of cellular internalisation of liposomes delivered siRNA and effects on siRNA engagement with target mRNA and silencing in cancer cells
por: Alshehri, Abdullah, et al.
Publicado: (2018)

Silencing of HMGA2 by siRNA Loaded Methotrexate Functionalized Polyamidoamine Dendrimer for Human Breast Cancer Cell Therapy
por: Abedi Gaballu, Fereydoon, et al.
Publicado: (2021)

MMP-2 Silencing through siRNA Loaded Positively-Charged Nanoparticles (AcPEI-NPs) Counteracts Chondrocyte De-Differentiation
por: Conte, Raffaele, et al.
Publicado: (2023)

Functionalized selenium nanoparticles for targeted delivery of doxorubicin to improve non-small-cell lung cancer therapy
por: Xia, Yu, et al.
Publicado: (2018)

Disulfide-Based Poly(amido amine)s for siRNA Delivery: Effects of Structure on siRNA Complexation, Cellular Uptake, Gene Silencing and Toxicity
por: Vader, Pieter, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_o00vtos4oqga4f4v18ul8c9l0m