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Andrographolide emeliorates maltol aluminium-induced neurotoxicity via regulating p62-mediated Keap1-Nrf2 pathways in PC12 cells
CONTEXT: Andrographolide (Andro) has a neuroprotective effect and a potential for treating Alzheimer’s disease (AD), but the mechanism has not been elucidated. OBJECTIVE: The efficacy of Andro on p62-mediated Kelch-like ECH-associated protein 1(Keap1)-Nuclear factor E2 related factor 2 (Nrf2) pathwa...
Autores principales: | Lu, Jiaqi, Gu, Lili, Li, Qin, Wu, Ningzi, Li, Hongxing, Zhang, Xinyue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919883/ https://www.ncbi.nlm.nih.gov/pubmed/33632062 http://dx.doi.org/10.1080/13880209.2021.1883678 |
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